Water → 2-((Triphenylmethyl)amino)ethanol

HRID 80299

반응식

HRID 80299 반응식
[C:1]1([C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:21][CH:22](O)[CH3:23].[OH2:25]>C(#N)C>[C:1]1([C:7]([NH:21][CH2:22][CH2:23][OH:25])([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 6456Trityl chlorideHCID 522583Acetaldehyde ammonia

생성물 1

HCID 31256082-((Triphenylmethyl)amino)ethanol수율 39%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Triphenylchloromethane (1.00 g, 3.58 mmol) (Wako Pure Chemical Industries, Ltd.) and aminoethanol (2.00 g, 32.7 mmol) were dissolved in acetonitrile (5 mL), and the solution was stirred at room temperature overnight. Water (100 mL) was poured into the reaction solution, and the precipitates were suction-filtered and then dried. The solid product was recrystallized from a mixed solvent of ethanol (Wako Pure Chemical Industries, Ltd.) and water, to thereby obtain the title compound (0.43 g, 39% yield).

후처리

  1. filtrationthe precipitates were suction-filtered
  2. customdried
  3. customThe solid product was recrystallized from a mixed solvent of ethanol (Wako Pure Chemical Industries, Ltd.) and water

출처 및 근거

ORD 기록
ord-c8024df5c705406a8ff8676a83e574f1
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846012B2

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