proline dl-form → 4-(5-Amino-isoquinoline-6-yloxy)-piperidin-1-carboxylic acid tert-butyl ester
반응식
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][CH:25]([O:28][c:29]2[c:30]([Br:39])[c:31]3[cH:32][cH:33][n:34][cH:35][c:36]3[cH:37][cH:38]2)[CH2:26][CH2:27]1.[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cu:41][I:42].[N-:11]=[N+:12]=[N-:13].[Na+:14].[Na+:2].[OH-:1].[OH2:40].[OH:3][C:4]([CH:5]1[CH2:8][CH2:7][CH2:6][NH:10]1)=[O:9]>>[NH2:10][c:30]1[c:29]([O:28][CH:25]2[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]2)[cH:38][cH:37][c:36]2[c:31]1[cH:32][cH:33][n:34][cH:35]2
