1-Bromopropane → Allyl 2,6-dimethylphenyl ether

HRID 893002

반응식

HRID 893002 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[OH:9].[OH-].[K+].Br[CH2:13][CH2:14][CH3:15]>CS(C)=O.O>[CH2:15]([O:9][C:3]1[C:4]([CH3:8])=[CH:5][CH:6]=[CH:7][C:2]=1[CH3:1])[CH:14]=[CH2:13]

참가 물질

6

반응물 3

HCID 78401-BromopropaneHCID 113352,6-DimethylphenolHCID 14797Potassium Hydroxide

생성물 1

HCID 641277Allyl 2,6-dimethylphenyl ether

시약·촉매·용매 2

HCID 679Dimethyl Sulfoxide용매HCID 962Water용매

실험 절차

2,6-Dimethylphenol (1.22 g) is added to a mixture of powdered potassium hydroxide (2.24 g) in dimethylsulfoxide (20 ml). Then 3-bromopropane (2.42 g) is added at 20°-25° and stirred for 0.5 hr. The mixture is diluted with water (100 ml) and extracted with methylene chloride (3×). The organic extracts are washed with water (2×) and then with saline, dried over sodium sulfate and concentrated under reduced pressure to give 1-allyloxy-2,6-dimethylbenzene.

후처리

  1. extractionextracted with methylene chloride (3×)
  2. washThe organic extracts are washed with water (2×)
  3. dry with materialwith saline, dried over sodium sulfate
  4. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-0fe4d1456ed94000808e602f72f1060a
출처 데이터셋
uspto-grants-1992_06
특허 번호
US05120843

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