Hydrochloric Acid → HCID 178525592, 화합물
반응식
[C:1]([CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([C:3]([OH:5])=[O:4])=O.Cl.[NH2:14][OH:15].[OH-].[Na+].Cl>O>[C:3]([C:1](=[N:14][OH:15])[CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([OH:5])=[O:4]참가 물질
6
실험 절차
A solution of 1-oxalomethyl-1H-tetrazole-5-thiol (10.0 g) and hydroxylamine hydrochloride (4.8 g) in water (100 ml) was adjusted to pH 6.0 with 2 N aqueous solution of sodium hydroxide and stirred at room temperature for 3.5 hours. The solution was acidified with 10% hydrochloric acid to pH 2.0, extracted with a mixture of tetrahydrofuran and ethyl acetate (1:1). The extract was washed with a saturated aqueous solution of sodium chloride, dried over magnesium sulfate and evaporated to give 1-(2-carboxy-2-hydroxyiminoethyl)-1H-tetrazole-5-thiol (5.61 g).
후처리
- extractionextracted with a mixture of tetrahydrofuran and ethyl acetate (1:1)
- washThe extract was washed with a saturated aqueous solution of sodium chloride
- dry with materialdried over magnesium sulfate
- customevaporated
출처 및 근거
- ORD 기록
- ord-25d0dc8900ee403aa4d85672e1ccb93c
- 출처 데이터셋
- uspto-grants-1983_12
- 특허 번호
- US04420477
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