반응식
OCCN(CC)CC.[NH2:9][C:10]1[CH:15]=[C:14]([NH2:16])[CH:13]=[CH:12][C:11]=1[S:17]([OH:20])(=[O:19])=[O:18].[F:21][C:22]1[C:27]([C:28]#[N:29])=[C:26]([F:30])[C:25]([F:31])=[C:24]([C:32]#[N:33])[C:23]=1F>CS(C)=O>[NH2:9][C:10]1[CH:15]=[C:14]([NH:16][C:23]2[C:24]([C:32]#[N:33])=[C:25]([F:31])[C:26]([F:30])=[C:27]([C:28]#[N:29])[C:22]=2[F:21])[CH:13]=[CH:12][C:11]=1[S:17]([OH:20])(=[O:18])=[O:19]참가 물질
5
반응 조건
- 온도
- 75 °C
실험 절차
To a mixture of N-(β-hydroxyethyl)diethylamine (5.86 g) and 2,4-diaminobenzene sulphonic acid (7.52 g) in dimethylsulphoxide (45 cm3) was added 1,2,4,5-tetrafluoro-3,6-dicyanobenzene (8.25 g) portionwise with stirring. The mixture was heated at 75° C. for 4 hours then poured into ice/water (140 cm3) to give a solution of 2-amino-4-(2,4,5-trifluoro-3,6-dicyanophenylamino)benzene sulphonic acid.
출처 및 근거
- ORD 기록
- ord-c7f3dee0d4c940379f166986fddd4592
- 출처 데이터셋
- uspto-grants-1998_06
- 특허 번호
- US05759247
연결된 노트
불러오는 중…