Chloride → (2,4-Dichloro-pyrimidin-5-yl)-(2,3-difluoro-6-methoxy-phenyl)-methanol
Reaction equation
[Br:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH:11]([Mg+:12])([CH3:13])[CH3:14].[Cl-:10].[F:15][c:16]1[c:17]([CH:18]=[O:19])[c:20]([O:25][CH3:26])[cH:21][cH:22][c:23]1[F:24]>>[c:2]1([CH:18]([c:17]2[c:16]([F:15])[c:23]([F:24])[cH:22][cH:21][c:20]2[O:25][CH3:26])[OH:19])[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-5822e1729919486f9589acb064514d04
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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