反应详情

温度

110 °C

A mixture of 0.5 g of 6-chloronicotinamide and 3 ml of 1-ethylpiperazine was stirred at 110° C. for 2 hours. The reaction solution was diluted with ethyl acetate, washed with water and then dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to afford 0.10 g of the title compound.

1. washwashed with water
2. dry with materialdried over anhydrous sodium sulfate
3. distillationThe solvent was distilled off under reduced pressure