Hydrochloric Acid → HCID 22666516, compound

HRID 1007886Notes

Reaction equation

HRID 1007886 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[C:9]([CH2:10][CH2:11][O:12][CH2:13][CH2:14][N:15]([CH3:17])[CH3:16])[C:2]1=2.[ClH:18]>C(OCC)(=O)C>[ClH:18].[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[C:9]([CH2:10][CH2:11][O:12][CH2:13][CH2:14][N:15]([CH3:16])[CH3:17])[C:2]1=2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22666392HCID 22666392, compound

Product 1

HCID 22666516HCID 22666516, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

In 2.5 mL of ethyl acetate is dissolved 0.49 g of N-[2-(2-benzo[b]thiophen-7-ylethoxy)ethyl]-N,N-dimethylamine, to which is added 0.73 mL of 3.5 mol/L solution of dry hydrogen chloride in ethyl acetate. The resulting solution is stirred at ambient temperature for one hour. The deposited crystal is collected by filtration, washed with ethyl acetate and dried to obtain 0.44 g of N-[2-(2-benzo[b]thiophen-7-ylethoxy)ethyl]-N,N-dimethylamine hydrochloride.

Workup

  1. filtrationThe deposited crystal is collected by filtration
  2. washwashed with ethyl acetate
  3. customdried

Sources & evidence

ORD record
ord-e5abbae765734f4586d7e2406d8f314f
Source dataset
uspto-grants-2004_09
Patent number
US06797726B1

Reaction notes

Loading…