Hydrochloric Acid → 74975-02-3

Temperature

20 °C

To a stirred solution of 2,2-dimethyl-4-[(E)-2-(methyloxy)ethenyl]tetrahydro-2H-pyran (2.93 g, 17.21 mmol) in THF (15 ml) was added 2N HCl (15 ml, 30.0 mmol) and the mixture was stirred at 20° C. After 1 hour the mixture was extracted with diethyl ether (3×25 ml); the combined ether extracts dried (Na2SO4), filtered and evaporated in vacuo (at 50 mbar and water bath at 15° C.) to give the title compound as a pale yellow oil (2.56 g).

1. extractionAfter 1 hour the mixture was extracted with diethyl ether (3×25 ml)
2. dry with materialthe combined ether extracts dried (Na2SO4)
3. filtrationfiltered
4. customevaporated in vacuo (at 50 mbar and water bath at 15° C.)

ORD record

ord-0db80cf53d7649618c8257dd5e7a6e9a

Source dataset

uspto-grants-2011_07

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07977344B2