Triethylamine → HCID 23159782, compound

HRID 1011435Notes

Reaction equation

HRID 1011435 reaction equation
C[S:2]([C:4]1[CH:5]=[N:6][C:7]2[C:12]([CH:13]=1)=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][CH:8]=2)=O.C(OC(C(F)(F)F)=O)(C(F)(F)F)=O.CCN(CC)CC>C(Cl)Cl>[CH3:15][O:14][C:11]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:12]=1[CH:13]=[C:4]([SH:2])[CH:5]=[N:6]2

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 9845Trifluoroacetic anhydrideHCID 23159787HCID 23159787, compound

Product 1

HCID 23159782HCID 23159782, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
35 °C

Procedure

To a solution of 3-(methylsulfinyl)-5-methoxyquinoline (2.21 g, 10 mmol) in CH2Cl2 (50 mL) is added TFAA. The resulting solution is stirred at 20-50° C. for 1 hour. The solution is then treated with NEt3 affording the title compound.

Sources & evidence

ORD record
ord-fcc3396e5bc64003a33717bb5420ebf3
Source dataset
uspto-grants-2011_07
Patent number
US07977354B2

Reaction notes

Loading…