反应详情

Methacryloyl chloride (50 ml, 0.5 mol) was added to a suspension of 133.5 g (1 mol) AlCl3 in 500 ml CH2Cl2 at −78° C. and stirred for 20 min. Then 59 g (0.5 mol) indane was added at the same temperature. The mixture was allowed to warm to room temperature and then was stirred overnight. Next day the mixture obtained was poured carefully into a mixture of ice (1000 g) and HCl (200 ml). The organic phase was separated, washed with water and 5% NaHCO3, and dried over MgSO4. Solvent was evaporated and residue was distilled in vacuum giving 77.6 g of product (83%), b.p. 118-120° C./0.5 torr.

1. stirringwas stirred overnight
2. customNext day the mixture obtained
3. customThe organic phase was separated
4. washwashed with water and 5% NaHCO3
5. dry with materialdried over MgSO4
6. customSolvent was evaporated
7. distillationresidue was distilled in vacuum