Acetic Acid → tert-butyl N-(1-cyclohexyl-4-diazo-3-oxobutan-2-yl)carbamate

HRID 102969Notes

Reaction equation

HRID 102969 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([C:10](=[O:11])[OH:12])[CH2:13][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:20][N:21]1[CH2:22][CH2:23][O:24][CH2:25][CH2:26]1.[CH3:43][C:44](=[O:45])[OH:46].[Cl:27][C:28]([O:29][CH2:30][CH:31]([CH3:32])[CH3:33])=[O:34].[N+:35](=[N-:36])=[CH2:37]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([C:10](=[O:12])[CH:37]=[N+:35]=[N-:36])[CH2:13][CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 79724-MethylmorpholineHCID 8028TetrahydrofuranHCID 9550DiazomethaneHCID 62365Isobutyl chloroformateHCID 2817530Boc-DL-Cha-OH

Product 1

HCID 72745943tert-butyl N-(1-cyclohexyl-4-diazo-3-oxobutan-2-yl)carbamate

Sources & evidence

ORD record
ord-2773ee0ba43e46a3ab42b0580f3a8a62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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