Hydrochloric Acid → HCID 19822237, compound

HRID 1030410Notes

Reaction equation

HRID 1030410 reaction equation
[C:1]([O:4][C:5]1[C:6]([CH3:37])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:27][O:28][C:29]1[CH:34]=[CH:33][C:32](N)=[CH:31][CH:30]=1)([CH2:17][CH2:18][CH:19]([CH3:26])[CH2:20][CH2:21][CH2:22][CH:23]([CH3:25])[CH3:24])[CH2:9][C:8]2=[O:36])(=[O:3])[CH3:2].N([O-])=O.[Na+].[ClH:42].[C:43]([O:47][CH2:48][CH3:49])(=[O:46])[CH:44]=[CH2:45]>>[C:1]([O:4][C:5]1[C:6]([CH3:37])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:27][O:28][C:29]1[CH:34]=[CH:33][C:32]([CH2:45][CH:44]([Cl:42])[C:43]([O:47][CH2:48][CH3:49])=[O:46])=[CH:31][CH:30]=1)([CH2:17][CH2:18][CH:19]([CH3:26])[CH2:20][CH2:21][CH2:22][CH:23]([CH3:25])[CH3:24])[CH2:9][C:8]2=[O:36])(=[O:3])[CH3:2]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 8821Ethyl AcrylateHCID 19822175HCID 19822175, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 19822237HCID 19822237, compound

Procedure

Following the same procedure as described in Preparation 18, 1.6 g of 6-acetoxy-2-(4-aminophenoxymethyl)-2-(3,7-dimethyloctyl)-5,7,8-trimethylchroman-4-one (prepared as described in Preparation 32), 0.28 g of sodium nitrite, 1.7 ml of concentrated hydrochloric acid, 3.3 ml of ethyl acrylate and 0.1 g of cuprous oxide were reacted, to give the title compound.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-d08ebcc91ded4d1c95001c0f2c66d51f
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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