Hydrochloric Acid → HCID 19822236, compound

HRID 1030418Notes

Reaction equation

HRID 1030418 reaction equation
[C:1]([O:4][C:5]1[C:6]([CH3:28])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:18][O:19][C:20]1[CH:25]=[CH:24][C:23](N)=[CH:22][CH:21]=1)([OH:17])[CH2:9][C:8]2=[O:27])(=[O:3])[CH3:2].[ClH:29].N([O-])=O.[Na+].[C:34]([O:38][CH2:39][CH3:40])(=[O:37])[CH:35]=[CH2:36]>O.CC(C)=O>[C:1]([O:4][C:5]1[C:6]([CH3:28])=[C:7]2[C:12](=[C:13]([CH3:16])[C:14]=1[CH3:15])[O:11][C:10]([CH2:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([CH2:36][CH:35]([Cl:29])[C:34]([O:38][CH2:39][CH3:40])=[O:37])=[CH:22][CH:21]=1)([OH:17])[CH2:9][C:8]2=[O:27])(=[O:3])[CH3:2]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 8821Ethyl AcrylateHCID 19822248HCID 19822248, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 19822236HCID 19822236, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

Following the same procedure as described in Preparation 18, 3.4 g of 6-acetoxy-2-(4-aminophenoxymethyl)-2-hydroxy-5,7,8-trimethylchroman-4-one (prepared as described in Preparation 44), 40 ml of acetone, 5 ml of 35% w/v aqueous hydrochloric acid, 1.2 g of sodium nitrite, 1.6 ml of water, 13 g of ethyl acrylate and 0.32 g of cuprous oxide were reacted, to give the title compound.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-91513605f0cd40b888afac0097e68913
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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