Hydrochloric Acid → 8-(3-(1-(4-Chlorophenyl)-2-(pyridin-4-yl)ethyl)phenyl)-6-isopropylquinoline

HRID 103132Notes

Reaction equation

HRID 103132 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[CH:5]([CH:6]([c:7]1[cH:8][c:9](-[c:13]2[cH:14][c:15]([CH:23]([CH3:24])[CH3:25])[cH:16][c:17]3[cH:18][cH:19][cH:20][n:21][c:22]23)[cH:10][cH:11][cH:12]1)[c:26]1[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]1)[c:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1)[CH3:39].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:48][CH2:49][OH:50].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[ClH:42].[Na+:41].[OH-:40]>>[CH2:5]([CH:6]([c:7]1[cH:8][c:9](-[c:13]2[cH:14][c:15]([CH:23]([CH3:24])[CH3:25])[cH:16][c:17]3[cH:18][cH:19][cH:20][n:21][c:22]23)[cH:10][cH:11][cH:12]1)[c:26]1[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]1)[c:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 208149663-(4-Chloro-phenyl)-3-[3-(6-isopropyl-quinolin-8-yl)-phenyl]-2-pyridin-4-yl-propionic acid ethyl ester

Product 1

HCID 101831968-(3-(1-(4-Chlorophenyl)-2-(pyridin-4-yl)ethyl)phenyl)-6-isopropylquinoline

Sources & evidence

ORD record
ord-9484c59dbcd64e5b89758382f9d2acfe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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