Dimethylformamide → HCID 19024785, compound

HRID 1034052Notes

Reaction equation

HRID 1034052 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]([C:22]2[CH:27]=[CH:26][C:25]([CH2:28][CH:29]([CH3:31])[CH3:30])=[CH:24][CH:23]=2)[CH2:12][C:13]2[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].C(Cl)(=O)C([Cl:35])=O.CN(C)C=O>ClCCl>[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]([C:22]2[CH:27]=[CH:26][C:25]([CH2:28][CH:29]([CH3:31])[CH3:30])=[CH:24][CH:23]=2)[CH2:12][C:13]2[CH:21]=[CH:20][C:16]([C:17]([Cl:35])=[O:18])=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 19024738HCID 19024738, compound

Product 1

HCID 19024785HCID 19024785, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
20 °C

Procedure

To a solution of 4-[2,2-bis(4-isobutylphenyl)ethyl]benzoic acid (400 mg) in dichloromethane (10 ml) were added oxalyl chloride (0.1 ml) and a drop of N,N-dimethylformamide at 0° C. After stirred at 20° C. for 1 hour, the,mixture was evaporated to give 4-[2,2-bis(4-isobutylphenyl)ethyl]benzoyl chloride (450 mg) as pale yellow oil.

Workup

  1. customat 0° C
  2. customthe,mixture was evaporated

Sources & evidence

ORD record
ord-c76f800a6ebb4d7aaee44843fad9cec2
Source dataset
uspto-grants-1994_05
Patent number
US05312829

Reaction notes

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