反应详情

To a stirred solution of 2-bromomethyl-acrylic acid methyl ester (1 g, 5.59 mmol) in dry CH3CN (20 ml) was added 2M solution of dimethylamine in THF (3.07 ml, 6.14 mmol) followed by K2CO3 (0.93 g, 6.7 mmol). The reaction mixture was stirred overnight, filtered and washed with CH2Cl2. The filtrate was concentrated. The crude product was used in next reaction without further purification.

1. filtrationfiltered
2. washwashed with CH2Cl2
3. concentrationThe filtrate was concentrated
4. customThe crude product was used in next reaction without further purification