Dimethylformamide → 5-nitro-N4-[(trans-4-pyrrolidin-1-ylcyclohexyl)methyl]-N2-[2-(trifluoromethoxy)benzyl]pyrimidine-2,4-diamine
Reaction equation
[Br:32][CH2:33][CH2:34][CH2:35][CH2:36][Br:37].[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46].[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][NH:9][c:10]2[n:11][c:12]([NH:19][CH2:20][c:21]3[c:22]([O:27][C:28]([F:29])([F:30])[F:31])[cH:23][cH:24][cH:25][cH:26]3)[n:13][cH:14][c:15]2[N+:16](=[O:17])[O-:18])[CH2:6][CH2:7]1.[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[N:1]1([CH:2]2[CH2:3][CH2:4][CH:5]([CH2:8][NH:9][c:10]3[n:11][c:12]([NH:19][CH2:20][c:21]4[c:22]([O:27][C:28]([F:29])([F:30])[F:31])[cH:23][cH:24][cH:25][cH:26]4)[n:13][cH:14][c:15]3[N+:16](=[O:17])[O-:18])[CH2:6][CH2:7]2)[CH2:33][CH2:34][CH2:35][CH2:36]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9981c169bdc54caf8533899fc518c3d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…