Oxalyl chloride → HCID 21390659, compound

HRID 1047337Notes

Reaction equation

HRID 1047337 reaction equation
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].C(C1[CH:15]=[CH:14][C:13]([S:16]([N:19]=[N+:20]=[N-:21])(=[O:18])=[O:17])=[CH:12][CH:11]=1)(O)=O>CN(C)C=O>[N:19]([S:16]([C:13]1[CH:14]=[CH:15][C:1]([C:2]([Cl:4])=[O:3])=[CH:11][CH:12]=1)(=[O:17])=[O:18])=[N+:20]=[N-:21]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 86999Benzoic acid, 4-(azidosulfonyl)-

Product 1

HCID 21390659HCID 21390659, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Under Argon at 0° C. and while stiffing, 0.7 ml oxalylchloride were added dropwise to a suspension of 908 mg (4 mmol) 4-carboxybenzene sulfonyl azide (Aldrich). The mixture was allowed to warm to room temperature. Then, 10 μl DMF (dimethylformamide) were added. After stirring for 1 h at room temp. a clear solution was formed. The solvent was removed using a rotary evaporator.

Workup

  1. customat 0° C.
  2. customwas formed
  3. customThe solvent was removed
  4. customa rotary evaporator

Sources & evidence

ORD record
ord-bc5e0c51a7e840eb8ab098d4faea2839
Source dataset
uspto-grants-2013_10
Patent number
US08569515B2

Reaction notes

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