Dimethylformamide → N-benzyl-N-cyclobutyl-4-(2-fluorophenyl)-2-morpholinopyrimidine-5-carboxamide
Reaction equation
[CH2:32]([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[NH:39][CH:40]1[CH2:41][CH2:42][CH2:43]1.[CH:44]([N:45]([CH:46]([CH3:47])[CH3:48])[CH2:49][CH3:50])([CH3:51])[CH3:52].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:7][CH2:8][Cl:9].[F:10][c:11]1[c:12](-[c:17]2[n:18][c:19]([N:26]3[CH2:27][CH2:28][O:29][CH2:30][CH2:31]3)[n:20][cH:21][c:22]2[C:23](=[O:24])[OH:25])[cH:13][cH:14][cH:15][cH:16]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57]>>[F:10][c:11]1[c:12](-[c:17]2[n:18][c:19]([N:26]3[CH2:27][CH2:28][O:29][CH2:30][CH2:31]3)[n:20][cH:21][c:22]2[C:23](=[O:24])[N:39]([CH2:32][c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[CH:40]2[CH2:41][CH2:42][CH2:43]2)[cH:13][cH:14][cH:15][cH:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7719d3ae1b864f6cbcac25f93f7f48c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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