Dimethylformamide → N-[5-[({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl)amino]-2-methylphenyl}-1-(2,6-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide

HRID 105271Notes

Reaction equation

HRID 105271 reaction equation
[CH3:85][CH2:86][O:87][C:88]([CH3:89])=[O:90].[CH:71]([N:72]([CH2:73][CH3:74])[CH:75]([CH3:76])[CH3:77])([CH3:78])[CH3:79].[Cl:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:16](=[O:17])[OH:18])[cH:12][cH:13][c:14]2=[O:15])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[NH2:19][c:20]1[cH:21][c:22]([NH:27][C:28](=[O:29])[NH:30][c:31]2[cH:32][c:33]([C:43]([CH3:44])([CH3:45])[CH3:46])[n:34][n:35]2-[c:36]2[cH:37][cH:38][c:39]([CH3:42])[cH:40][cH:41]2)[cH:23][cH:24][c:25]1[CH3:26].[O:80]=[CH:81][N:82]([CH3:83])[CH3:84].[P-:47]([F:48])([F:49])([F:50])([F:51])([F:52])[F:53].[n:54]1([O:55][C:56]([N:57]([CH3:58])[CH3:59])=[N+:60]([CH3:61])[CH3:62])[c:63]2[n:64][cH:65][cH:66][cH:67][c:68]2[n:69][n:70]1>>[Cl:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:16](=[O:18])[NH:19][c:20]3[cH:21][c:22]([NH:27][C:28](=[O:29])[NH:30][c:31]4[cH:32][c:33]([C:43]([CH3:44])([CH3:45])[CH3:46])[n:34][n:35]4-[c:36]4[cH:37][cH:38][c:39]([CH3:42])[cH:40][cH:41]4)[cH:23][cH:24][c:25]3[CH3:26])[cH:12][cH:13][c:14]2=[O:15])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 655011901-(2,6-Dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxylic acidHCID 670568481-(3-amino-4-methylphenyl)-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea

Product 1

HCID 25115849N-[5-[({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]amino]carbonyl)amino]-2-methylphenyl}-1-(2,6-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide

Sources & evidence

ORD record
ord-fe1884c8f0a34fdc88b407c96cd439cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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