Iodoethane → HCID 69792860, compound

HRID 1063095Notes

Reaction equation

HRID 1063095 reaction equation
[O:1]=[C:2]1[CH:8]([C:9]#[N:10])[C:7]2[CH:11]=[CH:12][CH:13]=[CH:14][C:6]=2[NH:5][C:4]2[CH:15]=[CH:16][CH:17]=[CH:18][C:3]1=2.C(=O)([O-])[O-].[K+].[K+].[CH2:25](I)[CH3:26]>CN(C=O)C>[CH2:25]([C:8]1[C:7]2[C:6]([N:5]3[C:4]4[CH:15]=[CH:16][CH:17]=[CH:18][C:3]=4[C:2](=[O:1])[NH:10][C:9]=13)=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH3:26]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 11031795HCID 11031795, compound

Product 1

HCID 69792860HCID 69792860, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 11-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-10-carbonitrile (500 mg, 2.13 mmol), potassium carbonate (359 mg, 2.6 mmole) and ethyl iodide (0.202 ml, 2.5 mmole) in 4 ml DMF is stirred at r.t. for 18 h.

Sources & evidence

ORD record
ord-15dea6e34f4b4f7e85b2f3bcc477c67d
Source dataset
uspto-grants-2005_11
Patent number
US06964960B2

Reaction notes

Loading…