Hydrochloric Acid → HCID 178520509, compound

HRID 1067666Notes

Reaction equation

HRID 1067666 reaction equation
Cl.C1(C(C)[CH2:9][N:10]=C=O)C=CC=CC=1.[C:14]1([CH:20](C)[CH2:21][NH2:22])C=CC=[CH:16][CH:15]=1.[O:24]=C(Cl)OC(Cl)(Cl)Cl>C(OCC)(=O)C>[NH:16]1[CH:15]=[C:14]([CH2:20][CH2:21][CH2:22][OH:24])[N:10]=[CH:9]1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 10426DiphosgeneHCID 113982-PhenylpropylamineHCID 211936242-Phenylpropyl isocyanate

Product 1

HCID 178520509HCID 178520509, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

HCl and 5 mmol of 2-phenylpropyl isocyanate (freshly prepared from 2-phenylpropylamine and diphosgene in ethyl acetate (Japan Kokai Tokkyo Koho JP, 60, 162, 262 (05.07.1985): Chem. Abstr. 103, 215012) are treated as described in Example 1.

Workup

  1. additionare treated

Sources & evidence

ORD record
ord-392568fb3fe447f386418e5d57b722a4
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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