4-Fluorobenzyl chloride → HCID 11447904, compound

HRID 1068524Notes

Reaction equation

C(P(CCCC)CCCC)CCC.[F:14][C:15]1[CH:22]=[CH:21][C:18]([CH2:19]Cl)=[CH:17][CH:16]=1.[Cl:23][SiH:24]([Cl:26])[Cl:25]>>[F:14][C:15]1[CH:22]=[CH:21][C:18]([CH2:19][Si:24]([Cl:26])([Cl:25])[Cl:23])=[CH:17][CH:16]=1

Participants

Reactant 3

HCID 96024-Fluorobenzyl chloride

HCID 13831Tributylphosphine

HCID 24811Trichlorosilane

Product 1

HCID 11447904HCID 11447904, compoundYield 96%

Procedure

In the same apparatus and procedure as Example 1 above, 0.15 g (0.75 mmol) of tri-n-butylphosphine, 1.08 g (7.5 mmol) of 4-fluorobenzyl chloride, and 5.08 g (37.5 mmol) of trichlorosilane were reacted at 150° C. for 2 hrs. The resulting mixture was distilled to give 1.6 g of (4-fluorobenzyl)trichlorosilane (bp; 56° C./13 mmHg, yield; 96%).

Workup

distillationThe resulting mixture was distilled

Sources & evidence

ORD record: ord-2e7e7a277d1a4bf9a292bb9e42116a0e
Source dataset: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06251057B1

Reaction notes

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