Benzyl Alcohol → phenylmethyl 6,11-dihydro-11-[1-[2-[4-(2-quinolinylmethoxy)phenyl]ethyl]-4-piperidinylidene]-5H-imidazo[2,1-b][3]benzazepine-3-carboxylate

HRID 107450Notes

Reaction equation

HRID 107450 reaction equation
[CH3:45][N:46]([CH3:47])[CH2:48][CH2:49][CH2:50][N:51]=[C:52]=[N:53][CH2:54][CH3:55].[CH3:64][N:65]([CH3:66])[c:67]1[cH:68][cH:69][n:70][cH:71][cH:72]1.[Cl:73][CH2:74][Cl:75].[ClH:44].[c:56]1([CH2:62][OH:63])[cH:57][cH:58][cH:59][cH:60][cH:61]1.[n:1]1[c:2]([CH2:11][O:12][c:13]2[cH:14][cH:15][c:16]([CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][C:24](=[C:27]4[c:28]5[n:29]([c:38]([C:41](=[O:42])[OH:43])[cH:39][n:40]5)[CH2:30][CH2:31][c:32]5[c:33]4[cH:34][cH:35][cH:36][cH:37]5)[CH2:25][CH2:26]3)[cH:17][cH:18]2)[cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12>>[n:1]1[c:2]([CH2:11][O:12][c:13]2[cH:14][cH:15][c:16]([CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][C:24](=[C:27]4[c:28]5[n:29]([c:38]([C:41](=[O:42])[O:43][CH2:62][c:56]6[cH:57][cH:58][cH:59][cH:60][cH:61]6)[cH:39][n:40]5)[CH2:30][CH2:31][c:32]5[c:33]4[cH:34][cH:35][cH:36][cH:37]5)[CH2:25][CH2:26]3)[cH:17][cH:18]2)[cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12

Participants

7

Reactant 6

HCID 244Benzyl AlcoholHCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 186124986,11-dihydro-11-[1-[2-[4-(2-quinolinylmethoxy)phenyl]ethyl]-4-piperidinylidene]-5H-imidazo[2,1-b][3]benzazepine-3-carboxylic acid

Product 1

HCID 18612500phenylmethyl 6,11-dihydro-11-[1-[2-[4-(2-quinolinylmethoxy)phenyl]ethyl]-4-piperidinylidene]-5H-imidazo[2,1-b][3]benzazepine-3-carboxylate

Sources & evidence

ORD record
ord-8e1448a8d01b49ccaaa81b1f3d3d0e12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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