Hydrochloric Acid → HCID 13061754, compound

HRID 1075298Notes

Reaction equation

HRID 1075298 reaction equation
[CH:1]([N:4]([C:9]1[CH:16]=[C:15]([CH3:17])[CH:14]=[CH:13][C:10]=1[C:11]#[N:12])[C:5](OC)=[O:6])([CH3:3])[CH3:2].[OH:18]O.Cl>C(O)C.[OH-].[Na+]>[CH:1]([N:4]1[C:9]2[C:10](=[CH:13][CH:14]=[C:15]([CH3:17])[CH:16]=2)[C:11](=[O:18])[NH:12][C:5]1=[O:6])([CH3:3])[CH3:2]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 784Hydrogen PeroxideHCID 13061753HCID 13061753, compound

Product 1

HCID 13061754HCID 13061754, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

To a suspension of 300 g 2-(N-isopropyl-N-carbomethoxyamino)-4-methyl-benzonitrile in 750 ml of ethanol and 234 ml 10N sodium hydroxide are added dropwise over 80 minutes 576 g of a 40% solution of hydrogen peroxide. The resulting clear solution is acidified with 195 ml of concentrated hydrochloric acid, whereupon the title compound precipitates, m.p. 250°-251°.

Sources & evidence

ORD record
ord-78ff9319128b4824b004d6edbe2fba76
Source dataset
uspto-grants-1983_07
Patent number
US04395550

Reaction notes

Loading…