Hydrochloric Acid → HCID 131710241, compound

HRID 1076671Notes

Reaction equation

HRID 1076671 reaction equation
[CH:1]1[C:6]2[N:7]=[C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][N:9]3[CH2:10][O:11][C:5]=2[CH:4]=[CH:3][CH:2]=1.[ClH:16].CCOCC>CC(O)C>[ClH:16].[CH:1]1[C:6]2[N:7]=[C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][N:9]3[CH2:10][O:11][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 12235832HCID 12235832, compound

Product 1

HCID 131710241HCID 131710241, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

To a solution of 1.0 g of 6H-pyrido [1,2-c][1,3,5]-benzoxadiazepine in 20 ml of 2-propanol is added 5.0 ml of 4.2N 2-propanolic hydrogen chloride. To the clear solution is added anhydrous ether until a turbidity forms. The pale yellow crystalline solid is filtered and recrystallized from acetonitrile to give about 1.0 g of the title compound, mp about 232°-234°.

Workup

  1. filtrationThe pale yellow crystalline solid is filtered
  2. customrecrystallized from acetonitrile

Sources & evidence

ORD record
ord-a17c4e21cd874a62b65d15ea37f1c7e2
Source dataset
uspto-grants-1976_05
Patent number
US03957806

Reaction notes

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