反应详情

A mixture of 18.2 g (0.05 mole) of 2,7-bis(3-chloropropionyl)xanthene, 2 g of potassium iodide, 100 ml. of diethylamine and 100 ml. of tetrahydrofuran was allowed to stand for 3 days then filtered. The filtrate was evaporated to dryness leaving a residue which was treated with 10% HCl and filtered. The filtrate was made alkaline, extracted with methylene chloride and treated with ethereal HCl. The resulting precipitate was filtered, recrystallized from methanol-diethyl ether and hydrated in a constant humidity chamber to give the desired product. M.P. 184.5°-185.5°C.

1. filtrationthen filtered
2. customThe filtrate was evaporated to dryness
3. customleaving a residue which
4. filtrationfiltered
5. extractionextracted with methylene chloride
6. additiontreated with ethereal HCl
7. filtrationThe resulting precipitate was filtered
8. customrecrystallized from methanol-diethyl ether and hydrated in a constant humidity chamber