2-Chloro-N,N-dimethylethylamine → HCID 12361782, compound

HRID 1077339Notes

Reaction equation

HRID 1077339 reaction equation
[CH3:1][N:2]([CH3:16])[CH:3]1[CH2:15][C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[CH2:5][CH2:4]1.[H-].[Na+].[CH3:19][N:20]([CH2:22][CH2:23]Cl)[CH3:21].C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl>CN(C)C=O>[CH3:1][N:2]([CH3:16])[CH:3]1[CH2:15][C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]([CH2:23][CH2:22][N:20]([CH3:21])[CH3:19])[C:6]=2[CH2:5][CH2:4]1

Participants

6

Reactant 4

HCID 79012-Chloro-N,N-dimethylethylamineHCID 24758Sodium hydrideHCID 36082CyclindoleHCID 149026Tetrafluoro-m-phenylenediamine dihydrochloride

Product 1

HCID 12361782HCID 12361782, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following the procedure given in Example 11 and using 6.7 g. of 3-(dimethylamino)-1,2,3,4-tetrahydrocarbazole, 1.35 g. of sodium hydride and 3.37 g. of dimethylaminoethyl chloride in 75 ml. of dimethylformamide there was otained 5.6 g. of 3-(dimethylaino)-9-[2-(dimethylamino)ethyl]-1,2,3,4-tetrahydrocarbazole in the form of its dihydrochloride salt which melted at 269°-270°C. (dec.) (corr.)

Sources & evidence

ORD record
ord-47fb61e34077483ea3f49f1817ea15e5
Source dataset
uspto-grants-1976_05
Patent number
US03959309

Reaction notes

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