反应详情

温度

100 °C

A mixture of m-fluoronitrobenzene (9 g) and piperidine (40 ml) was heated with stirring at 100° C. for 15 hours and to the mixture were added ethyl acetate ester (100 ml) and aqueous saturated solution of potassium carbonate (100 ml). The organic layer was washed with water and dried over anhydrous sodium sulfate. The solvent was distilled off to obtain N-(3-nitrophenyl)piperidine (13.5 g) as a yellow oily compound.

1. temperaturewas heated
2. washThe organic layer was washed with water
3. dry with materialdried over anhydrous sodium sulfate
4. distillationThe solvent was distilled off