Thiophene-3-carboxylic acid → HCID 23367108, compound

HRID 1079468Notes

Reaction equation

HRID 1079468 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]([OH:8])=O)=[CH:2]1.[N+]([O-])(O)=O.[O:13]([CH2:17][CH2:18][NH2:19])[N+:14]([O-:16])=[O:15].C(OC(C)C)(C)C>>[O:13]([CH2:17][CH2:18][NH:19][C:6]([C:3]1[CH:4]=[CH:5][S:1][CH:2]=1)=[O:8])[N+:14]([O-:16])=[O:15]

Participants

4

Reactant 3

HCID 6918Thiophene-3-carboxylic acidHCID 7914Diisopropyl EtherHCID 78397Ethanol, 2-amino-, 1-nitrate, nitrate (1:1)

Product 1

HCID 23367108HCID 23367108, compoundYield 35.2%

Procedure

Following a similar treatment to that in Example 2 and using 0.55 g of 3-thiophenecarboxylic acid and 0.60 g of nitroxyethylamine nitrate, 0.27 g of the title compound was obtained as colorless plates (solvent for recrystallization; diisopropyl ether).

Sources & evidence

ORD record
ord-a77e1b4627254fa3be1df8e8098ae84a
Source dataset
uspto-grants-1996_12
Patent number
US05580893

Reaction notes

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