4-Chloro-1,2-dinitrobenzene → HCID 2916373, compound

HRID 1081469Notes

Reaction equation

HRID 1081469 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([N+:11]([O-])=O)[CH:3]=1.N[CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>CCO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[C:4]([NH:11][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH:3]=1

Participants

4

Reactant 2

HCID 330974-Chloro-1,2-dinitrobenzeneHCID 4082852-Morpholinoethylamine

Product 1

HCID 2916373HCID 2916373, compoundYield 62.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 19.5 g of 4-chloro-1,2-dinitrobenzene and 35 g of 4-(2-aminoethyl)morpholine in 180 ml of EtOH is stirred for 20 hours at RT. The precipitate formed is filtered off and washed with iso ether to give 17.1 g of the expected product after crystallization twice in succession from isopropanol.

Workup

  1. customThe precipitate formed
  2. filtrationis filtered off
  3. washwashed with iso ether

Sources & evidence

ORD record
ord-8dc179927a5c41398e904a454ab0b5e2
Source dataset
uspto-grants-1996_12
Patent number
US05585394

Reaction notes

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