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HRID1085278

反应详情

EQUATION

反应方程式

HRID 1085278 的结构方程式

REACTANTS

反应物

3
结构：O=[N+]([O-])c1ccc(Cl)c(Cl)c1
HCID7443

3,4-Dichloronitrobenzene

C6H3Cl2NO2

结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：CCS(=O)(=O)N(CCCN1CCN(c2cc(=O)n(C)c(=O)n2C)CC1)c1ccc([N+](=O)[O-])cc1
HCID20061072

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(N2CCN(CCCNc3ccc([N+](=O)[O-])cc3Cl)CC2)cc(=O)n(C)c1=O
HCID20061247

未命名化合物

收率 155.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A mixture consisting of 0.4 g of Compound 158 obtained in Example 99-(1), 0.4 g of 3,4-dichloro-nitrobenzene, 0.43 ml of triethylamine and 6 ml of dimethylformamide was treated in a manner similar to Example 99-(2), thereby obtaining 0.55 g of 1,3-dimethyl-6-{4-[3-(2-chloro-4-nitroanilino)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione.

WORKUP

后处理

  1. additionwas treated in a manner similar to Example 99-(2)