1-Phenylpiperazine → HCID 15636953, compound

HRID 1087844Notes

Reaction equation

HRID 1087844 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH:8]=[CH:7][CH2:6][CH2:5]1.[C:10](N1C=CN=C1)(N1C=CN=C1)=[O:11].[C:22]1([N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>O1CCCC1>[C:22]1([N:28]2[CH2:33][CH2:32][N:31]([C:10]([NH:1][CH2:2][CH2:3][N:4]3[CH2:5][CH:6]=[CH:7][CH2:8][CH2:9]3)=[O:11])[CH2:30][CH2:29]2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

5

Reactant 3

HCID 70961-PhenylpiperazineHCID 682631,1'-CarbonyldiimidazoleHCID 15636952HCID 15636952, compound

Product 1

HCID 15636953HCID 15636953, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following the procedure of Example 5, N-(2-aminoethyl)-1,2,3,6-tetrahydropyridine and 1,1'-carbonyldiimidazole are reacted together in tetrahydrofuran and the product thereof is reacted further with 1-phenylpiperazine to give the title compound.

Sources & evidence

ORD record
ord-688d35277aae48a6b39479344db1b456
Source dataset
uspto-grants-1990_10
Patent number
US04960776

Reaction notes

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