2-Bromophenol → HCID 15058601, compound

HRID 1087884Notes

Reaction equation

HRID 1087884 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].C(=O)([O-])[O-].[K+].[K+].Br[CH2:16][CH2:17][F:18]>CN(C)C=O>[F:18][CH2:17][CH2:16][O:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Br:1]

Participants

5

Reactant 3

HCID 72442-BromophenolHCID 11430Potassium CarbonateHCID 129822-Fluoroethyl bromide

Product 1

HCID 15058601HCID 15058601, compoundYield 77.1%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a manner similar to that disclosed in German Offenlegungschrift DE No. 3,402,483, the reaction of 5.0 grams (0.029 mole) of 2-bromophenol, 6.0 grams (0.043 mole) of potassium carbonate, and 5.5 grams (0.03 mole) of 1-bromo-2-fluoroethane in 50 ml of N,N-dimethylformamide yielded 4.9 grams of 2-bromophenyl 2-fluoroethyl ether as an oil.

Sources & evidence

ORD record
ord-f94651e5f9184654b83e6f980afe9322
Source dataset
uspto-grants-1990_10
Patent number
US04960884

Reaction notes

Loading…