反应详情

温度

80 °C

Ethanol (20 cm3) was added portionwise to a suspension of finely divided sodium (10.0 g) in dry toluene (100 cm3). On completion of the addition the mixture was heated for 3.5 hours at 80° C. To the resulting yellow suspension, cooled to 20° C., was added dropwise, over a period of 1 hour, a mixture of diethyl succinate (70.0 g) and ethyl formate (35.0 g), whilst the temperature of the mixture was maintained in the range 20° to 30° C. The mixture was kept at the ambient temperature for 16 hours after which water (100 cm3) was added carefully.

1. additionOn completion of the addition the mixture
2. temperatureTo the resulting yellow suspension, cooled to 20° C.
3. additionwas added dropwise, over a period of 1 hour
4. temperaturewhilst the temperature of the mixture was maintained in the range 20° to 30° C