2,2,6,6-Tetramethylpiperidine → HCID 178418821, compound

HRID 1089911Notes

Reaction equation

HRID 1089911 reaction equation
C([Li:5])CCC.[CH3:6][C:7]1([CH3:15])[CH2:12][CH2:11][CH2:10][C:9]([CH3:14])([CH3:13])[NH:8]1>C1CCCCC1.O1CCCC1>[Li:5][N:8]1[C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11][CH2:12][C:7]1([CH3:15])[CH3:6]

Participants

5

Reactant 2

HCID 130352,2,6,6-TetramethylpiperidineHCID 178418339Butyllithium

Product 1

HCID 178418821HCID 178418821, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 8078CyclohexaneSolvent

Procedure

A solution of 0.17 mole of lithium 2,2,6,6-tetramethyl piperidide is prepared by the addition of 0.17 mole of n-butyllithium (2.3 moles) in 74 ml of cyclohexane to 0.17 mole (28.7 ml) of 2,2,6,6-tetramethylpiperidine in 120 ml of tetrahydrofuran at a temperature below -20° C.

Sources & evidence

ORD record
ord-3babfa32ffc340808c71308d40d3d4b6
Source dataset
uspto-grants-1992_01
Patent number
US05079363

Reaction notes

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