Dimethylformamide dimethyl acetal → HCID 53684638, compound

HRID 1090070Notes

Reaction equation

HRID 1090070 reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][C:6]([C:7]([C:9]2[C:10]([CH3:18])=[C:11]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:13][CH:14]=2)=[O:8])=[CH:5][CH:4]=1.[CH3:21][N:22]([CH:24](OC)OC)[CH3:23]>CN(C=O)C>[CH3:21][N:22]([CH3:24])[CH:23]=[CH:18][C:10]1[C:9]([C:7](=[O:8])[C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:20][CH:19]=2)=[CH:14][CH:13]=[CH:12][C:11]=1[N+:15]([O-:17])=[O:16]

Participants

4

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 14535915(4-Methoxyphenyl)(2-methyl-3-nitrophenyl)methanone

Product 1

HCID 53684638HCID 53684638, compoundYield 91.9%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 97.9 g (0.36 mole) of 3-(4-methoxybenzoyl)-2-methylnitrobenzene and 191 ml (1.45 mole) of DMF dimethyl acetal in 400 ml of DMF was heated under reflux for about nineteen hours and the reaction mixture then taken to dryness in vacuo to give 108 g of 2-(2-dimethylaminoethenyl)-3-(4-methoxybenzoyl)nitrobenzene as a red oil.

Workup

  1. temperatureunder reflux for about nineteen hours

Sources & evidence

ORD record
ord-e179de2e60dd4e74833ea07d89a75eb0
Source dataset
uspto-grants-1992_01
Patent number
US05081122

Reaction notes

Loading…