Potassium Carbonate → HCID 57743258, compound

HRID 1095179Notes

Reaction equation

HRID 1095179 reaction equation
[F:1][C:2]1[CH:9]=[C:6]([CH:7]=[O:8])[C:5]([OH:10])=[CH:4][CH:3]=1.[O:11]1[CH2:16][CH2:15][CH:14](OS(C)(=O)=O)[CH2:13][CH2:12]1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:10][CH:14]2[CH2:15][CH2:16][O:11][CH2:12][CH2:13]2)=[C:6]([CH:9]=1)[CH:7]=[O:8]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 27373285-FluorosalicylaldehydeHCID 11344352Oxan-4-yl methanesulfonate

Product 1

HCID 57743258HCID 57743258, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In a manner similar to the method described in Example 4a, 5-fluoro salicylaldehyde (Aldrich) reacted with methanesulfonic acid tetrahydro-pyran-4-yl ester (Example 32a) and potassium carbonate in dimethylformamide to give a solid. MS (H+), 225.

Workup

  1. customto give a solid

Sources & evidence

ORD record
ord-aa629a5f62184a9ea2080a3f92e37679
Source dataset
uspto-grants-2012_03
Patent number
US08134001B2

Reaction notes

Loading…