反应详情

To ethyl 7-(2-methoxyethoxy)imidazo[1,2-a]pyridine-3-carboxylate (5.01 g, 19.0 mmol) in THF/EtOH (32/6 mL) was added lithium hydroxide (37.9 ml, 37.9 mmol), and the reaction was stirred overnight. HCl (57 mmol, 2M in ether) was added to the mixture, followed by concentration to give the desired product.

1. concentrationfollowed by concentration