HRID1096933
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
To a solution of tert-Butyl 6-(2-{[(2,2-dimethylpropanoyl)oxy]methyl}-2H-tetrazol-5-yl)-4-oxo-spiro[chroman-2,4′-piperidine]-1′-carboxylate (68.0 g) in EtOAc (1.36 L) was added 4N HCl in EtOAc (340 ml) at 0° C. and the mixture was further stirred for 21 h at room temperature. The resulted precipitate was filtered and washed with EtOAc to give intended compound as a pale yellow solid.
WORKUP
后处理
- filtrationThe resulted precipitate was filtered
- washwashed with EtOAc
- customto give