反应详情

温度

70 °C

The mixture of 5-bromo-3-methyl-1-phenyl-1H-indazole (642 mg), Pd(OAc)2 (52 mg), DPPF (123 mg), diisopropyl ethyl amine (1.14 ml) in DMF (5 ml)-MeOH (5 ml) was purged with CO and stirred at 70° C. under CO atmosphere for over night. The cooled reaction mixture was evaporated and the residue was purified by silica gel column chromatography (hexane/EtOAc) to give the title compound as brown oil.

1. customwas purged with CO
2. customThe cooled reaction mixture
3. customwas evaporated
4. customthe residue was purified by silica gel column chromatography (hexane/EtOAc)