HCID 63675640, compound → HCID 178422846, compound

HRID 1104907Notes

Reaction equation

HRID 1104907 reaction equation
Cc1ccc2c(cnn2C2CCCCO2)c1Br.F[B-](F)(F)c1ccc2ncccc2c1.[K+]>CC#N.CC(=O)[O-].CC(=O)[O-].CCc1cc(CC)cc(CC)c1.CCc1cccc(CC)c1.COc1cccc(OC)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.Cc1ccccc1.O.O=P([O-])([O-])[O-].[K+].[K+].[K+].[Pd+2]>Cc1ccc2c(cnn2C2CCCCO2)c1-c1ccc2ncccc2c1

Participants

12

Reactant 2

HCID 63675640HCID 63675640, compoundHCID 71307646HCID 71307646, compound

Product 1

HCID 178422846HCID 178422846, compoundYield 46.71%

Reagents, catalysts & solvents 9

HCID 62657Potassium Phosphate, TribasicReagentHCID 167845palladium(II) acetateCatalystHCID 112698722-Dicyclohexylphosphino-2',6'-dimethoxybiphenylCatalystHCID 962WaterSolvent3×HCID 1140TolueneSolventHCID 6342AcetonitrileSolventHCID 76021,3,5-TriethylbenzeneSolventHCID 88641,3-DiethylbenzeneSolventHCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-d083678b288b4b1a9d4d6306dbe40dc4
Source dataset
Rapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
Original link
View source

Reaction notes

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