4-Hydroxybenzaldehyde → HCID 136025196, compound

HRID 1106106Notes

Reaction equation

HRID 1106106 reaction equation
[C:1]1([N:7]2[C:11](=[O:12])[CH2:10][C:9]([C:13](=[O:15])[NH2:14])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH:16][C:17]1[CH:24]=[CH:23][C:20]([CH:21]=O)=[CH:19][CH:18]=1.[Cl-].[Na+]>CN(C)C=O>[C:1]1([N:7]2[C:11](=[O:12])[C:10](=[CH:21][C:20]3[CH:23]=[CH:24][C:17]([OH:16])=[CH:18][CH:19]=3)[C:9]([C:13](=[O:15])[NH2:14])=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 1264-HydroxybenzaldehydeHCID 5234Sodium ChlorideHCID 808131H-Pyrazole-3-carboxamide, 4,5-dihydro-5-oxo-1-phenyl-

Product 1

HCID 136025196HCID 136025196, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

20.5 g (0.1 mole) of 1-phenyl-3-carbamoyl-2-pyrazolin-5-one and 12.2 g (0.1 mole) of p-hydroxybenzaldehyde were stirred for 1 hour in 100 ml of boiling dimethylformamide. The hot reaction mixture was poured out in 500 ml of an aqueous solution of sodium chloride (12%). After stirring and standing for a while, the yellow dye was filtered with suction, rinsed with water, and washed with hot acetone.

Workup

  1. filtrationthe yellow dye was filtered with suction
  2. washrinsed with water
  3. washwashed with hot acetone

Sources & evidence

ORD record
ord-80ddd21c63314ee693a17d935229acc0
Source dataset
uspto-grants-1982_01
Patent number
US04311787

Reaction notes

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