Triethylamine → 2-Ethylphenyl isocyanate

HRID 1107442Notes

Reaction equation

HRID 1107442 reaction equation
[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5])[CH3:2].CCN(CC)CC.Cl[C:18](Cl)([O:20]C(=O)OC(Cl)(Cl)Cl)Cl>C(Cl)Cl>[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[N:5]=[C:18]=[O:20])[CH3:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 113572-EthylanilineHCID 94429Triphosgene

Product 1

HCID 5834862-Ethylphenyl isocyanate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The compound was prepared substantially in accordance with the procedure detailed in Example 27A, using 2-ethylaniline (1.5 ml, 12.2 mmol), Et3N (4.3 ml, 30.4 mmol) and triphosgene (1.2 g, 4.0 mmol) in 45 ml of CH2Cl2.

Workup

  1. customThe compound was prepared substantially in accordance with the procedure

Sources & evidence

ORD record
ord-c7c70eca27844f6c928a46b5928c8106
Source dataset
uspto-grants-2000_05
Patent number
US06060484

Reaction notes

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