2-Chloroethanol → 2-Chloroethyl 2-(4-chlorophenoxy)-2-methylpropionate

HRID 1111776Notes

Reaction equation

HRID 1111776 reaction equation
[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([O:6][C:7]([CH3:12])([CH3:11])[C:8]([OH:10])=[O:9])=[CH:4][CH:3]=1.[Cl:15][CH2:16][CH2:17]O.Cl>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][C:7]([CH3:12])([CH3:11])[C:8]([O:10][CH2:17][CH2:16][Cl:15])=[O:9])=[CH:13][CH:14]=1

Participants

4

Reactant 3

HCID 342-ChloroethanolHCID 313Hydrochloric AcidHCID 2797Clofibric Acid

Product 1

HCID 1040992-Chloroethyl 2-(4-chlorophenoxy)-2-methylpropionate

Procedure

107.3 g (0.5 mole) of p-chlorophenoxy-2-methylpropionic acid are dissolved in 241.5 g (3 moles) of 2-chloroethanol. The solution is saturated with HCl gas. The excess of solvent is distilled under 11 Torr. The ester is distilled under 0.02 Torr, at a temperature of 97°-98°.

Workup

  1. distillationThe excess of solvent is distilled under 11 Torr
  2. distillationThe ester is distilled under 0.02 Torr, at a temperature of 97°-98°

Sources & evidence

ORD record
ord-5a954809def746cda2a29a76c1b5ad42
Source dataset
uspto-grants-1978_10
Patent number
US04118583

Reaction notes

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