Chloride → 1-(6-(6-methoxypyridin-3-ylamino)-5-(2-methyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-3-yl)-2,2-dimethylpropan-1-ol

HRID 1113301Notes

Reaction equation

HRID 1113301 reaction equation
[C:35]([CH3:36])([CH3:37])([CH3:38])[Mg+:39].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[n:11][cH:12][c:13]([CH:14]=[O:15])[cH:16][c:17]2-[c:18]2[c:19]3[n:20][cH:21][n:22]([CH:28]4[O:29][CH2:30][CH2:31][CH2:32][CH2:33]4)[c:23]3[n:24][c:25]([CH3:27])[n:26]2)[cH:7][n:8]1.[CH3:46][OH:47].[Cl-:34].[ClH:40]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[n:11][cH:12][c:13]([CH:14]([OH:15])[C:35]([CH3:36])([CH3:37])[CH3:38])[cH:16][c:17]2-[c:18]2[c:19]3[n:20][cH:21][n:22]([CH:28]4[O:29][CH2:30][CH2:31][CH2:32][CH2:33]4)[c:23]3[n:24][c:25]([CH3:27])[n:26]2)[cH:7][n:8]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 313Hydrochloric AcidHCID 887MethanolHCID 8028TetrahydrofuranHCID 59548351HCID 59548351, compoundHCID 178448412HCID 178448412, compound

Product 1

HCID 665999591-(6-(6-methoxypyridin-3-ylamino)-5-(2-methyl-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-3-yl)-2,2-dimethylpropan-1-ol

Sources & evidence

ORD record
ord-4b0d33fbb965411fa3aee5c53a091d8a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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