Tetrahydrofuran → Benzyl [4-(4-iodophenyl)but-3-yn-1-yl]carbamate
Reaction equation
[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH2:62]([O:63][C:64](=[O:65])[NH:66][CH2:67][CH2:68][C:69]#[CH:70])[c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[CH3:118][CH2:119][N:120]([CH2:121][CH3:122])[CH2:123][CH3:124].[CH3:14][O:15][C:16](=[O:17])[CH:18]([NH:19][C:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:41]1)([c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)[c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)[CH2:54][O:55][c:56]1[cH:57][cH:58][c:59]([CH2:26][CH2:27][CH2:28][CH2:29][NH:30][C:31](=[O:32])[O:33][CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:60][cH:61]1.[I:6][c:7]1[cH:8][cH:9][c:10]([I:13])[cH:11][cH:12]1.[Pd:77]([Cl:78])[Cl:79].[c:80]1([P:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[cH:94][cH:95][cH:96][cH:97][cH:98]1.[c:99]1([P:100]([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[cH:113][cH:114][cH:115][cH:116][cH:117]1>>[c:7]1([C:26]#[C:27][CH2:28][CH2:29][NH:30][C:31](=[O:32])[O:33][CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:8][cH:9][c:10]([I:13])[cH:11][cH:12]1Participants
8
Sources & evidence
- ORD record
- ord-526f100b90fc43569d29834e03ac5401
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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