Hydrochloric Acid → 2-(3-Cyclohexyl-5-fluoro-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:19][c:20]([F:22])[cH:21]1)[C:10]([CH3:29])([CH3:30])[CH2:9]2.[CH3:36][OH:37].[ClH:35].[Li+:33].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[OH-:32].[OH2:31].[OH2:34]>>[O:3]=[C:4]([OH:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[cH:17][c:18]([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:19][c:20]([F:22])[cH:21]1)[C:10]([CH3:29])([CH3:30])[CH2:9]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9a5872ecb76b4918bb2741ebb9209902
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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