Ethyl formate → 1-Boc-4-[(1-methyl-4-piperidyl)methyl]piperidine
Reaction equation
[Al+3:22].[CH:27]([O:28][CH2:29][CH3:30])=[O:31].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[CH2:5][CH2:6]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[N:1]1([CH3:27])[CH2:2][CH2:3][CH:4]([CH2:7][CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[CH2:5][CH2:6]1Participants
7
Sources & evidence
- ORD record
- ord-4d2549c3260d4622bad307c4b2d81459
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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